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  Post-marketing of disease modifying drugs in multiple sclerosis: an exploratory analysis of gender effect in interferon beta treatment

summary: Interferon beta is one of the accepted disease modifying treatments for MS. The authors studied MS treatment in a large Italian population with MS for up to seven years. They focused on the comparison between men and women in terms of response to treatment. Their results suggest that men and women seem to have different ways of responding to treatment, since men showed a lower risk than women of experiencing a first relapse after the onset of treatment but a higher risk for experiencing an increase in their level of disability.

authors: Trojano M, Pellegrini F, Paolicelli D, Fuiani A, Zimatore GB, Tortorella C, Simone IL, Patti F, Ghezzi A, Portaccio E, Rossi P, Pozzilli C, Salemi G, Lugaresi A, Bergamaschi R, Millefiorini E, Clerico M, Lus G, Vianello M, Avolio C, Cavalla P, Iaffaldano P, Direnzo V, D'Onghia M, Lepore V, Livrea P, Comi G, Amato MP; on behalf of Italian Multiple Sclerosis Database Network (MSDN) group

source: J Neurol Sci. 2009 Jul 15

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category: Clinical Trials and Therapeutics

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glossary:

    Disability
    Interferon
    Multiple sclerosis
    Physical
    Relapse
    Sclerosis
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