summary: In adult-onset multiple sclerosis, major depression, fatigue and psychological distress are common, however there is little information in children with MS. The authors studied 56 children with MS with self-assessment scales of fatigue or depression and specific neuropsychological interviews. They found significant fatigue in 11 children and 12 children received a formal psychiatric diagnosis. Moreover, having MS affected school activities in 28% of cases, daily living activities in 41% and social relationships in 28%. This study confirmed the critical role of psychosocial difficulties in children and adolescents with MS.

authors: Goretti B, Ghezzi A, Portaccio E, Lori S, Zipoli V, Razzolini L, Moiola L, Falautano M, De Caro MF, Viterbo R, Patti F, Vecchio R, Pozzilli C, Bianchi V, Roscio M, Comi G, Trojano M, Amato MP.

source: Neurol Sci. 2010 May 8

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