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summary: The authors review the role and the mechanism of action of JC virus in causing progressive multifocal leukoencephalopathy, a serious but rare adverse event that recently occurred in two patients with MS involved in a clinical trial with Natalizumab.
authors: Khalili K, White MK, Lublin F, Ferrante P, Berger JR.
source: Neurology. 2007 Mar 27;68(13):985-90.
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category: Virology
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glossary:
Clinical trial
Multiple sclerosis
Sclerosis
Virus
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