summary: The aim of this study was to assess longitudinally cognitive functioning in people with relapsing-remitting multiple sclerosis (RRMS) and its relationship with clinical and MRI variables. Early RRMS patients and matched healthy controls were assessed in parallel in three testing sessions over 3 years, using a specific battery of neuropsychological tests. They also underwent an MRI analysis. The authors concluded that a cognitive deterioration could be expected in approximately one-third of MS patients with relatively short disease duration.

authors: Amato MP, Portaccio E, Goretti B, Zipoli V, Iudice A, Della Pina D, Malentacchi G, Sabatini S, Annunziata P, Falcini M, Mazzoni M, Mortilla M, Fonda C, De Stefano N.

source: Mult Scler. 2010 Aug 20. [Epub ahead of print]

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