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  Remyelination capacity of the MS brain decreases with disease chronicity

summary: MS is an inflammatory-demyelinating disease of the central nervous system. It is known that demyelinated areas can recover the myelin by an internal repair mechanism of the damaged neural tissue by a process called remyelination. However, little is known about the characteristics of this protective process. The authors of this study aimed to investigate the frequency of remyelination in people with MS with different disease durations and the areas where this protective phenomenon was more prominent. They finally conclude that remyelination was more prominent in earlier stages of the disease and also that the location of the lesion may influence the extent of the remyelination.

authors: Goldschmidt T, Antel J, König FB, Brück W, Kuhlmann T

source: Neurology. 2009 Jun 2;72(22):1914-21

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category: Pathology

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glossary:

    Brain
    Central nervous system
    Chronic
    Computerized
    Lesion
    Myelin
    Nervous system
    Plaque
    Remyelination
    Ribonucleic acid
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