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  The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors.

summary: The authors looked at the mechanism of action of FTY720, a promising new potential treatment for MS. They found that, in addition to its known immunosuppressive actions, it also prolongs the life of the early cells which later become oligodendrocytes, the cells which produce myelin.

authors: Coelho RP, Payne SG, Bittman R, Spiegel S, Sato-Bigbee C.

source: J Pharmacol Exp Ther. 2007 Aug 28

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category: Clinical Trials and Therapeutics

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glossary:

    Cell
    Immunoglobulin
    Immunosuppressio
    Myelin
    Oligodendrocyte
    Oligodendrocyte
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