summary: The authors studied safety and effectiveness of high dose beta-interferon in people with MS who did not respond to standard treatment. They found that higher doses of beta-interferon were more effective in reducing inflammation on MRI but further studies are needed to see if this reduces relapses.

authors: Durelli L, Barbero P, Bergui M, Versino E, Bassano MA, Verdun E, Ferrero B, Rivoiro C, Ferrero C, Picco E, Ripellino P, Viglietti D, Giuliani G, Montanari E, Clerico M; for the OPTIMS Study Group

source: J Neurol. 2008 Sep 25 [Epub ahead of print]

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