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  The role of SVZ-derived neural precursors in demyelinating diseases: From animal models to multiple sclerosis

summary: The authors review the role of stem cells, found in the brains of adults, in the process of myelin repair in animal models of multiple sclerosis, and in post-mortem studies in people. Preliminary studies suggest that these cells are activated in response to the disease process and contribute to the repair of demyelinated lesions. Further studies are needed to shed light on the nature of their action.

authors: Nait-Oumesmar B, Picard-Riéra N, Kerninon C, Baron-Van Evercooren A.

source: J Neurol Sci. 2008 Feb 15;265(1-2):26-31.

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category: Cell Biology

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glossary:

    Animal models
    Brain
    Cell
    Lesion
    Multiple sclerosis
    Myelin
    Plaque
    Sclerosis
    Stem cell
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