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  The role of the CD58 locus in multiple sclerosis

summary: In this study the authors have investigated the protective role of some variants of a gene which has recently been associated with the risk of MS and with the function of the regulatory T cells.

authors: De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, Hu X, Ashley CW, Choy E, Rioux JD, Pericak-Vance MA, Ivinson A, Booth DR, Stewart GJ, Palotie A, Peltonen L, Dubois B, Haines JL, Weiner HL, Compston A, Hauser SL, Daly MJ, Reich D, Oksenberg JR, Hafler DA

source: Proc Natl Acad Sci USA. 2009 Feb 23

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category: Genetics

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glossary:

    Cell
    Gene
    Multiple sclerosis
    Sclerosis
    T-cell
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