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summary: This rat study looked at the mechanisms of axonal degeneration, the process thought to be responsible for accumulating disability in MS, and found evidence that nitric oxide pathways may be involved. These could have potential to be a future therapeutic target.
authors: Aboul-Enein F, Weiser P, Hoftberger R, Lassmann H, Bradl M.
source: Acta Neuropathol (Berl). 2006 Jun;111(6):539-47. Epub 2006 Apr 25.
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category: Pathogens
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glossary:
Acute
Axon
Demyelination
Disability
Experimental
Gene
Myelin
Myelitis
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