summary: MS is a complex disease in which genes may play a role. In this study the authors aimed to investigate the relative contribution of genes and the environment to the appearance of MS by re-analysing six published studies from six countries, on people with MS who were twins. The authors found that the different methodologies and the huge variability in the results of the different studies prevented them from obtaining robust conclusions. They also suggested that further twin studies with improved methodology should be undertaken in people with MS, to more thoroughly investigate the genetic influence in the appearance of MS.

authors: Hawkes Ch, Macgregor A

source: Mult Scler. 2009 Jun;15(6):661-7

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category: Genetics

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