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  Vitamin D status and effect of low-dose cholecalciferol and high-dose ergocalciferol supplementation in multiple sclerosis

summary: Vitamin D metabolism has been frequently related to the risk of MS, though its relationship remains unknown. In this study the authors have seen that the levels of vitamin D in a large group of people with MS were insufficient in more than the 80% of them. Moreover, even with high doses of vitamin D, optimal levels were only achieved in less than the 40% of the people. The authors of this study suggest that further studies are needed to better understand the complex relationship between vitamin D and MS, and the possible need of vitamin D replacement.

authors: Hiremath G, Cettomai D, Baynes M, Ratchford J, Newsome S, Harrison D, Kerr D, Greenberg B, Calabresi P

source: Mult Scler. 2009 Apr 21

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category: Epidemiology

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