summary: The reason that MS is more common in women than men is incompletely understood. The authors looked to see if it was due to differences in which X chromosome is inactivated, a process which occurs normally in all women. They found no evidence that this contributed to the development of MS, but small differences were seen in the different subtypes.

authors: Knudsen GP, Harbo HF, Smestad C, Celius EG, Akesson E, Oturai A, Ryder LP, Spurkland A, Orstavik KH.

source: Eur J Neurol. 2007 Dec;14(12):1392-6. Epub 2007 Oct 26.

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