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  Drugs commonly used in MS that affect sexual functioning
MS in focus Issue 6 - 2006

Drugs commonly used in MS that affect sexual functioning Although changes in sexual desire, performance and satisfaction often occur as a result of MS, they may also be a consequence of some medications. (Currently, the vast majority of the side-effects listed below are noted by manufacturers to be "infrequent" or "rare".)

DrugSymptoms treatedDrug effect on sexual function

FluoxetineDepression
Decreased libido
Uncontrollable laughing or crying
Delayed or absent ejaculation
Fatigue
Inability to achieve orgasm (known as anorgasmia)
Persisting, painful erection of the penis occurring without sexual stimulation (known as priapism) Anyone experiencing this should seek medical help immediately
Menstrual irregularities
Secretion of breast milk (known as hyperprolactinaemia or galactorrhoea)

FluvoxamineDepressionDecreased libido
Delayed or absent ejaculation
Sertraline Depression
Decreased libido
Inability to achieve orgasm
Menstrual irregularities
Enlarged or painful breasts
Irritation of the vaginal lining (vaginitis)
Inflammation of the head of the penis and foreskin
Secretion of breast milk Paroxetine
Depression
Decreased libido
Delayed or absent ejaculation
Inability to achieve orgasm
Secretion of breast milk

CitalopramDepressionDecreased libido
Delayed or absent ejaculation
Inability to achieve orgasm

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