A Web-based tool for personalised prediction of long-term disease course in patients with multiple sclerosis

This study group looked at the first web-based prognostic calculator in MS which is capable of delivering individualised estimates of disease progression, called the Evidence-Based Decision Support Tool in Multiple Sclerosis (EBDiMS).

The researchers compared the predictive accuracy and consistency of EBDiMS with that of 17 neurologists specialised in MS. They found that whilst the predictive accuracy was similar, neurologists showed a significant intra-rater and inter-rater variability.

The authors concluded that as EBDiMS was consistent, it is of superior utility in a specialised setting. They also noted that further field testing of EBDiMS in non-specialist settings, and investigation of its usefulness for counselling patients in treatment decisions, is warranted.

Authors: Galea I, Lederer C, Neuhaus A

Source: Eur J Neurol. 2012 Dec 7. doi: 10.1111/ene.12016. [Epub ahead of print]

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