Can the ABILHAND handle manual ability in MS?


In this study, the researchers looked at the suitability of the 23-item ABILHAND (developed for stroke) as a potential outcome measure for clinical research and trials in MS.

The ABILHAND is a PRO instrument that purports to measure manual ability, defined as the capacity to manage daily activities using the upper limbs, regardless of the strategies involved. Both traditional and modern (Rasch) psychometric methods were used to analyse the data from 300 people.

The traditional psychometric methods implied ABILHAND as a robust manual ability PRO measure for MS. The Rasch model supported this finding. Both evaluations supported ABILHAND as a robust manual ability PRO measure for MS. Rasch measurement methods were more informative than traditional psychometric methods. Also, it was more consistent in detecting anomalies and identified ways of advancing further ABILHAND’s measurement performance to reduce any potential for type II errors in clinical trials.

Authors: Barrett L, Cano S, Zajicek J

Source:
Mult Scler. 2012 Oct 24. [Epub ahead of print]

Read the abstract

 

Latest MS research news

Main MS research areas

Challenges of MS research

Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial