Latest MS research news

Latest MS research news | 05 November 2013

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus

This study looked at two risk alleles found in the TNFRSF1A locus that are associated with MS susceptibility.

From MSIF

Latest MS research news | 05 November 2013

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in rats

Studies have shown inflammation in the outer covering of the brain in patients with secondary progressive MS. This study shows that certain molecules which promote inflammation are involved.

From MSIF

Latest MS research news | 29 October 2013

Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: The DEFINE study

This study reports the effects of BG-12 on measures of health-related quality of life (HRQoL) over two years of treatment in the Phase III DEFINE study population.

From MSIF

Latest MS research news | 29 October 2013

Sex as a determinant of relapse incidence and progressive course of multiple sclerosis

This study looked at the relationship between gender differences in the incidence of MS relapses as well as the relationship between sex and primary progressive disease course on a large international observatory cohort: the MSBase registry.

From MSIF

Latest MS research news | 29 October 2013

Effects of exercise on fitness and cognition in progressive MS: a randomised, controlled pilot trial

This pilot randomised-controlled trial looked at the potential benefit of standardised exercise as a therapeutic intervention in progressive MS.

From MSIF

Latest MS research news | 21 October 2013

Teriflunomide versus subcutaneous interferon beta-1a in patients with RRMS: a randomised, controlled phase 3 trial

Teriflunomide selectively and reversibly inhibits dihydro-orotate dehydrogenase (DHODH). DHODH is a mitochrondrial enzyme involved in pyrimidine synthesis required by ...

From MSIF

Latest MS research news | 21 October 2013

Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with MS

This study looked at the changes in total lymphocyte counts (TLCs) in the peripheral blood of 23 people with MS receiving fingolimod for four to seven years, as well as the association between TLCs and T-cell subsets ...

From MSIF

Latest MS research news | 21 October 2013

Ribosomal protein S6 mRNA is a biomarker upregulated in MS, downregulated by interferon treatment, and affected by season

In this Australian study, the researchers tested if T-cell activation gene expression pattern (TCAGE) in whole blood was replicated in an independent sample ...

From MSIF

Latest MS research news | 14 October 2013

Dalfampridine improves walking speed, walking endurance, and community participation in veterans with MS: a longitudinal cohort study

This longitudinal study looked at the tolerability as well as the effects of dalfampridine on walking and community participation.

From MSIF

Latest MS research news | 14 October 2013

A novel internet-based method of capturing outcomes in MS

This study from the UK looked at a novel internet-based method of capturing outcomes in 81 people with MS who were having EDSS assessments as part of clinical trials.

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial