Latest MS research news

Latest MS research news | 18 June 2013

Tobacco smoking and disability progression in MS: UK cohort study

This study demonstrated that regular smoking is associated with more severe disease as well as faster progression of disability. Stopping smoking either before or after the onset of MS is associated with slower progression of disability.

From MSIF

Latest MS research news | 18 June 2013

Confounding underlies the apparent month of birth effect in MS

Several groups have previously reported the apparent seasonal patterns for month of birth suggested to be specific to MS, that is to say increased in those born in spring and reduced in the winter. The analysis carried out by this study group indicates that the apparent seasonal patterns for month of birth are expected by chance alone and so are probably false positives.

From MSIF

Latest MS research news | 18 June 2013

Magnetic resonance frequency shifts during acute MS lesion formation

The researchers looked at a new imaging technique on the MRI scanner which detects an increase in frequency shifts of the MR signal. They found that the increase in MR frequency was seen one month before and one month after contrast enhanced lesions appeared on conventional MRI.

From MSIF

Latest MS research news | 10 June 2013

Interleukin-12p40 in the spinal fluid as a biomarker for clinically isolated syndrome

This study demonstrates the potential use of a specific biomarker in the cerebrospinal fluid which may be of use in the future to help in the diagnostic process of MS.

From MSIF

Latest MS research news | 10 June 2013

MRI lesions as a surrogate for relapses in multiple sclerosis: a meta-analysis of randomised trial

This analysis looked at 31 previous trials and extracted data on the treatment effects on MRI lesions and on relapse from each trial. They found that the effect of a treatment on relapses can be accurately predicted by the effect of that therapy on MRI lesions.

From MSIF

Latest MS research news | 10 June 2013

Assessing dalfampridine efficacy in the physician's office

This review article looks at dalfampridine, which has been shown to improve walking speed in people with MS. The trials which have taken place were based on consistency and not magnitude of response, therefore not making it applicable to physicians in a clinic setting. Alternatives were suggested.

From MSIF

Latest MS research news | 04 June 2013

Immunosuppressive therapy reduces axonal damage in progressive MS

This study from Sweden looked at biomarkers in the cerebrospinal fluid in people with progressive forms of MS and the impact of immunosuppressive therapy (mitoxantrone or rituximab) on these markers.

From MSIF

Latest MS research news | 04 June 2013

Neuro-ophthalmologic evaluation, quality of life, and functional disability in people with MS.

This study found that people with relapsing-remitting MS had a progressive decline in retinal nerve fibre layer thickness over time, indicating progressive axonal loss, with a lower quality of life and more functional disability.

From MSIF

Latest MS research news | 04 June 2013

Mycophenolate mofetil in multiple sclerosis: a multicentre retrospective study on 344 patients

This retrospective study looked at the efficacy and safety of mycophenolate mofetil (MMF), which is commonly used after organ transplantation to prevent graft rejection. The researchers found a positive effect of MMF on MS relapse and the treatment was quite well tolerated overall.

From MSIF

Latest MS research news | 28 May 2013

Predictive value of one month retinal nerve fiber layer thinning for deficits at six months after acute optic neuritis

The retinal nerve fibre layer (RNFL) was assessed in people with acute optic neuritis. The study group found a correlation between RNFL at 1 month and 6 months, suggesting that by 1 month, permanent injury has already occurred in the affected eyes.

From MSIF
 

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