Latest MS research news

Latest MS research news | 15 April 2013

Wallerian and trans-synaptic degeneration contribute to optic radiation damage in multiple sclerosis: a diffusion tensor MRI study

This study group from Italy explored the contribution of local and distant mechanisms associated with optic radiation (OR) damage in MS.

From MSIF

Latest MS research news | 15 April 2013

Cognitive reserve and cortical atrophy in multiple sclerosis: a longitudinal study

This study tested the cognitive reserve (CR) hypothesis in the model of MS by assessing the interactions among CR, brain atrophy and cognitive efficiency in patients with RRMS.

From MSIF

Latest MS research news | 09 April 2013

Childhood body mass index and multiple sclerosis risk: a long-term cohort study

This prospective study from the US examined if body mass index (BMI) at ages 7-13 years was associated with MS risk among 302,043 individuals.

From MSIF

Latest MS research news | 09 April 2013

Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples

This paper looks at the association between antibody reactivity against Epstein-Barr nuclear antigen-1 (EBNA-1) and five EBNA-1 domains and the risk of MS.

From MSIF

Latest MS research news | 09 April 2013

Low myo-inositol indicating astrocytic damage in a case series of NMO

This study looked at five Neuromyelitis Optica (NMO)-related cases, with longitudinally extensive lesions in the upper cervical cord who underwent 1 H-MR spectroscopy of the cervical cord.

From MSIF

Latest MS research news | 02 April 2013

Timed 25-Foot Walk: Direct evidence that improving 20% or greater is clinically meaningful in MS

This study group used data from two phase III clinical trials of dalfampridine (fampridine outside the US) in 533 patients with MS and looked at the clinical meaningfulness of the Timed 25-Foot Walk (T25FW) changes.

From MSIF

Latest MS research news | 02 April 2013

A comparative study of CSF neurofilament light and heavy chain protein in MS

This research group from the UK compared two assays to measure two subunits of the neurofilament protein-neurofilament light (NfL) and neurofilament heavy chain (NfH). Neurofilaments are the major structural elements of neurons that are specifically expressed in ...

From MSIF

Latest MS research news | 02 April 2013

Brain atrophy and lesion load predict long term disability in multiple sclerosis

This large multicentre study looked at whether brain atrophy and lesion volumes predict subsequent 10 year clinical evolution in MS. The researchers looked at 261 MS patients with MR imaging at baseline and after 1-2 years, as well as EDSS at baseline ...

From MSIF

Latest MS research news | 26 March 2013

Reproduction and the risk of multiple sclerosis

This case-control study showed that patients with MS had fewer pregnancies and childbirths within five years before the year of clinical onset.

From MSIF

Latest MS research news | 26 March 2013

Safinamide and flecainide protect axons and reduce microglial activation in models of MS

In the experimental model of MS, the researchers demonstrated the potential of safinamide (a sodium channel blocking agent) as an affective neuroprotective agent in MS.

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial