Latest MS research news

Latest MS research news | 31 March 2014

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive MS (MS-STAT)

This phase 2, placebo-controlled trial showed that statins (simvastatin) in secondary progressive MS were safe, well tolerated and reduced progression of annualised brain atrophy over two years.

From MSIF

Latest MS research news | 25 March 2014

Core outcome measures for exercise studies in people with MS

The results of a meeting of a group of international experts, which recommended the most appropriate outcome measures for use in exercise-based research as one step in the process toward the application, and evaluation, of exercise in people with MS.

From MSIF

Latest MS research news | 25 March 2014

Tracking changes over time in retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness in MS

Eyes of people with MS provide a unique opportunity to study axonal degeneration. The study showed that there was progressive neuronal loss in patients in the absence of clinically evident inflammation in the eyes.

From MSIF

Latest MS research news | 24 March 2014

Serum phosphorylated neurofilament-heavy chain levels in MS patients

This study looked at a particular type of protein in the blood of patients with MS, as a serum biomarker of axonal injury which could prove useful as a prognostic or monitoring tool in the future.

From MSIF

Latest MS research news | 18 March 2014

Evaluating the response to glatiramer acetate in relapsing-remitting MS patients

This study shows that the presence of relapses, with or without MRI activity, in patients treated with glatiramer acetate identifies patients with a higher risk of developing new clinical activity and disability progression over the following years.

From MSIF

Latest MS research news | 18 March 2014

PET imaging of glucose metabolism, neuroinflammation and demyelination in the lysolecithin rat model for MS

The researchers in this study looked at specific disease processes in MS using positron-emission tomography (PET) imaging in small MS-like brain lesions in the rat model.

From MSIF

Latest MS research news | 18 March 2014

Major stressful life events in adulthood and risk of MS

This study looked at the risk of developing MS following exposure to well-defined indicators of severe stress as a result of divorce or loss of a close family member. The results demonstrated that there was no association between these stress measures and risk of developing MS.

From MSIF

Latest MS research news | 11 March 2014

Optical coherence tomography and visual evoked potentials

Optic neuritis occurs in about 50 per cent of MS patients. This study looked at visual evoked potentials, which assess the integrity and function of the visual pathway, and optical coherence tomography, which measures the retinal nerve fibre layer thickness.

From MSIF

Latest MS research news | 11 March 2014

Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes

This study looked at the prevalence of non-enhancing black holes on MRI in a large population of patients with a clinically isolated syndrome and to determine if they helped to better predict conversion to clinically definite MS.

From MSIF

Latest MS research news | 11 March 2014

MiR-126: a novel route for natalizumab action?

This study shows the potential role of a particular type of protein (miR-126), which control gene expression and are involved in immunity. This particular protein was found to be down-regulated in patients treated with natalizumab, while the protein was up-regulated during relapse.

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial