Latest MS research news

Latest MS research news | 02 April 2013

A comparative study of CSF neurofilament light and heavy chain protein in MS

This research group from the UK compared two assays to measure two subunits of the neurofilament protein-neurofilament light (NfL) and neurofilament heavy chain (NfH). Neurofilaments are the major structural elements of neurons that are specifically expressed in ...

From MSIF

Latest MS research news | 02 April 2013

Brain atrophy and lesion load predict long term disability in multiple sclerosis

This large multicentre study looked at whether brain atrophy and lesion volumes predict subsequent 10 year clinical evolution in MS. The researchers looked at 261 MS patients with MR imaging at baseline and after 1-2 years, as well as EDSS at baseline ...

From MSIF

Latest MS research news | 26 March 2013

Reproduction and the risk of multiple sclerosis

This case-control study showed that patients with MS had fewer pregnancies and childbirths within five years before the year of clinical onset.

From MSIF

Latest MS research news | 26 March 2013

Safinamide and flecainide protect axons and reduce microglial activation in models of MS

In the experimental model of MS, the researchers demonstrated the potential of safinamide (a sodium channel blocking agent) as an affective neuroprotective agent in MS.

From MSIF

Latest MS research news | 26 March 2013

Cognitive impairment differs between primary progressive and relapsing-remitting MS

The main finding in this study is the difference in frequency and severity of cognitive impairment between PPMS and RRMS patient groups. Patients with PPMS were more frequently impaired in executive function and verbal episodic memory

From MSIF

Latest MS research news | 19 March 2013

Distinction of seropositive NMO spectrum disorder and MS brain lesion distribution

In this study from the UK, the researchers looked at identifying differences in MRI brain lesion distribution between aquaporin-4 antibody-positive NMOSD (neuromyelitis optica and its spectrum disorder) and RRMS, using quantitative lesion mapping.

From MSIF

Latest MS research news | 19 March 2013

Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology

The researchers looked at a post-mortem cohort of pathologically confirmed cases with multiple sclerosis with fresh frozen material for genetic analysis and fixed material for pathology.

From MSIF

Latest MS research news | 19 March 2013

The changing clinical course of multiple sclerosis: A matter of grey matter

This study from Italy developed a five year longitudinal study looking at demographic, clinical and MRI parameters that could predict the changing clinical course of MS.

From MSIF

Latest MS research news | 12 March 2013

White-matter lesions drive deep gray-matter atrophy in early multiple sclerosis: support from structural MRI

The researchers looked at the relationship between lesions within the cerebral white matter (WM) and atrophy within the deep grey matter (GM) in MS.

From MSIF

Latest MS research news | 12 March 2013

Cognitive impairment in MS: Impact of white matter integrity, gray matter volume, and lesions

This study group from the Netherlands looked at the extent and severity of white matter (WM) damage, using diffusion tensor imaging (DTI), to distinguish cognitively preserved (CP) from cognitively impaired (CI) ...

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial