Latest MS research news

Latest MS research news | 04 December 2012

Impairment of JCV-specific T-cell response by corticotherapy: Effect on PML-IRIS management?

This study examined the net effects of corticosteroids (CS) on the virus-specific T-cell responses, especially JC virus, to determine the optimal timing of corticosteroid administration in patients with MS with natalizumab-caused PML-IRIS.

From MSIF

Latest MS research news | 04 December 2012

CSF inflammation and axonal damage are increased and correlate in progressive multiple sclerosis

This study looked at biomarkers of inflammation, axonal damage and demyelination in the CSF and to see if these biomarkers are associated with progressive MS.

From MSIF

Latest MS research news | 27 November 2012

Heat sensitive persons with multiple sclerosis are more tolerant to resistance exercise than to endurance exercise

This study looked at 16 heat sensitive people with MS, who were randomly allocated a session of resistance exercise (RE) and endurance exercise (EE) or EE and RE respectively.

From MSIF

Latest MS research news | 27 November 2012

Serial proton MR spectroscopy of gray and white matter in relapsing-remitting MS

The researchers recruited 18 patients with RRMS and performed T1 weighted, T2-weighted MRI and 3D proton magnetic resonance spectroscopic imaging (H-MRSI) every 6 months for 3 years.

From MSIF

Latest MS research news | 27 November 2012

Long-term outcome of paediatric-onset MS: a population-based study

This population based study from the UK looked at clinical features and accumulation of disability in paediatric-onset MS (<18 years) and compared it to a cohort of patients with adult-onset MS...

From MSIF

Latest MS research news | 20 November 2012

Multiple sclerosis: Oral BG12 for treatment of relapsing-remitting MS

This review article looks at two large phase III trials which looked at the clinical efficacy and safety profile of oral dimethyl fumarate (BG12) in patients with relapsing-remitting MS.

From MSIF

Latest MS research news | 20 November 2012

The month of birth effect in multiple sclerosis: systematic review, meta-analysis and effect of latitude

This interesting study from the UK looked at the month of birth as a risk factor for MS, which has previously been hypothesised to be related to maternal vitamin D levels during pregnancy.

From MSIF

Latest MS research news | 20 November 2012

Increased iron accumulation occurs in the earliest stages of demyelinating disease

his study from the UK looked at the use of ultra-high field (7T) MRI to detect iron deposition in the central nervous system and to assess iron concentration in the deep grey matter of patients having a clinically isolated syndrome.

From MSIF

Latest MS research news | 12 November 2012

Alemtuzumab for patients with relapsing MS after disease-modifying therapy: a randomised controlled phase 3 trial

This randomised controlled phase 3 trial assessed the efficacy and safety of alemtuzumab compared with interferon beta 1a in people with relapsing-remitting MS who have relapsed despite first-line treatment.

From MSIF

Latest MS research news | 12 November 2012

Time to secondary progression in patients with MS who were treated with first generation immunomodulating drugs

This study from Sweden looked at the time interval from onset to secondary progression (SP) in a cohort of contemporary RRMS patients treated with disease modifying therapy and a historical population-based incidence cohort.

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial