Latest MS research news

Latest MS research news | 22 January 2013

Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis

This study looked at quantitative diffusion tensor and magnetisation transfer imaging measures in the spinal cord to assess lesion burden with high and low disability. 124 people with MS underwent 3-T cervical spinal cord MRI.

From MSIF

Latest MS research news | 14 January 2013

Multiple Sclerosis: Validation of MR Imaging for Quantification and Detection of Iron

This study from Canada evaluated four MR imaging methods based on transverse relaxation (T2 weighted, 2 mapping, and R2* mapping) and phase imaging, for measuring iron in subcortical grey matter and for detecting iron within and surrounding MS lesions.

From MSIF

Latest MS research news | 14 January 2013

On the sex ratio of multiple sclerosis

This review article looks at the female-to-male ratio of MS, which is similar to other immune-mediated diseases, with the susceptibility higher in females than males.

From MSIF

Latest MS research news | 14 January 2013

Clinical effects of natalizumab on multiple sclerosis appear early in treatment course

The researchers looked at when the clinical effects of natalizumab become apparent in a phase II study, and the annualised relapse rates per 3-month period, and the time to first relapse in the phase III AFFIRM study and in the multinational Tysabri Observational Program.

From MSIF

Latest MS research news | 07 January 2013

MR imaging and cognitive correlates of relapsing-remitting multiple sclerosis patients with cerebellar symptoms

This study looked at the presence of neuroanatomical abnormalities in relapsing-remitting MS patients with cerebellar signs (RR-MSc), indicating damage to the cerebellum, and without cerebellar signs (RR-MSnc).

From MSIF

Latest MS research news | 07 January 2013

Spatial variability and changes of metabolite concentrations in the cortico-spinal tract in multiple sclerosis using coronal CSI

From MSIF

Latest MS research news | 07 January 2013

Long-term MRI findings in neuromyelitis optica: seropositive versus seronegative patients

In this study from Turkey, the researchers looked at the long-term MRI characteristics of seropositive and seronegative neuromyelitis optica (NMO) patients and considered the possible overlap with MS.

From MSIF

Latest MS research news | 17 December 2012

Location of brain lesions predicts conversion of clinically isolated syndromes to multiple sclerosis

This multi-centre, retrospective study looked at the relevance of brain lesion location and frequency in predicting 1-year conversion to MS.

From MSIF

Latest MS research news | 17 December 2012

MRI characteristics of familial and sporadic multiple sclerosis patients

This prospective study compared conventional and non-conventional MRI characteristics of patients with familial and sporadic MS. 758 patients were enrolled, with 25.9% who had a positive family history of MS.

From MSIF

Latest MS research news | 17 December 2012

Fingolimod treatment in multiple sclerosis leads to increased macular volume

This longitudinal study from America looked at the association of initiation of fingolimod and increased macular volume.

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial