Latest MS research news

Latest MS research news | 20 November 2012

The month of birth effect in multiple sclerosis: systematic review, meta-analysis and effect of latitude

This interesting study from the UK looked at the month of birth as a risk factor for MS, which has previously been hypothesised to be related to maternal vitamin D levels during pregnancy.

From MSIF

Latest MS research news | 20 November 2012

Increased iron accumulation occurs in the earliest stages of demyelinating disease

his study from the UK looked at the use of ultra-high field (7T) MRI to detect iron deposition in the central nervous system and to assess iron concentration in the deep grey matter of patients having a clinically isolated syndrome.

From MSIF

Latest MS research news | 12 November 2012

Alemtuzumab for patients with relapsing MS after disease-modifying therapy: a randomised controlled phase 3 trial

This randomised controlled phase 3 trial assessed the efficacy and safety of alemtuzumab compared with interferon beta 1a in people with relapsing-remitting MS who have relapsed despite first-line treatment.

From MSIF

Latest MS research news | 12 November 2012

Time to secondary progression in patients with MS who were treated with first generation immunomodulating drugs

This study from Sweden looked at the time interval from onset to secondary progression (SP) in a cohort of contemporary RRMS patients treated with disease modifying therapy and a historical population-based incidence cohort.

From MSIF

Latest MS research news | 12 November 2012

A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis

This] study from Dublin looked at the sensitivity of the diagnostic criteria for primary progressive MS.

From MSIF

Latest MS research news | 04 November 2012

Mechanisms of oxidative damage in MS and neurodegenerative diseases: therapeutic modulation via fumaric acid esters

This study reviews the role of oxidative stress in neurodegenerative conditions, in particular MS.

From MSIF

Latest MS research news | 04 November 2012

Segmentation of magnetization transfer ratio lesions for longitudinal analysis of demyelination and remyelination in MS

In this study from Canada, they demonstrate novel techniques for quantifying MTR (magnetization transfer ratio), by identifying focal areas of MTR decrease (MTR lesions) directly on paired MTR images.

From MSIF

Latest MS research news | 04 November 2012

Can the ABILHAND handle manual ability in MS?

In this study, the researchers looked at the suitability of the 23-item ABILHAND (developed for stroke) as a potential outcome measure for clinical research and trials in MS.

From MSIF

Latest MS research news | 29 October 2012

Switching therapy from natalizumab to fingolimod in relapsing-remitting MS: clinical and magnetic resonance imaging findings

This study from Italy looked at 22 people with relapsing-remitting MS with positive JC virus, who were switched from natalizumab to fingolimod after a three month washout period.

From MSIF

Latest MS research news | 29 October 2012

Evaluation of inner retinal layers in patients with MS or neuromyelitis optica using optical coherence tomography

This cross-sectional study from Brazil looked at the inner retinal layers in the macula using frequency domain optical coherence tomography (fd-OCT), in five different groups-controls, neuromyelitis optica (NMO), longitudinally extensive transverse myelitis (LETM), MS with a history of optic neuritis (MS-ON) and MS without a history of optic neuritis (MS non-ON).

From MSIF
 

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