Latest MS research news

Latest MS research news | 18 February 2014

Effect of oral cladribine on time to conversion to clinically definite MS

This trial for early signs of MS, investigated the effect of oral cladribine on conversion to clinically definite MS in patients with a first clinical demyelinating event, when given at the same doses shown to be effective in relapsing MS.

From MSIF

Latest MS research news | 18 February 2014

Neurofilament light antibodies in serum reflect response to natalizumab treatment in MS

This study group looked at components/proteins of neurons, and the role of antibodies against these proteins (neurofilament light protein), as biomarkers for monitoring response to treatment and their correlation with the different types of MS.

From MSIF

Latest MS research news | 18 February 2014

TIRC7 and HLA-DR axis contributes to inflammation in MS

This study looked at the role of a certain cell surface protein (TIRC7) in inflammation in MS. The results demonstrated that the activation of this protein resulted in the activation of lymphocyte proliferation which promotes inflammation in multiple sclerosis.

From MSIF

Latest MS research news | 11 February 2014

Diagnostic uncertainty during the transition to secondary progressive MS

This study looked at the diagnosis of the transition from relapsing remitting MS (RRMS) to secondary progressive MS (SPMS). A period of diagnostic uncertainty regarding the transition existed in many of the patients in this study.

From MSIF

Latest MS research news | 11 February 2014

Epstein-Barr virus-specific adoptive immunotherapy for progressive MS

A lot of evidence to date indicates that infection with Epstein-Barr virus (which causes glandular fever), has a role in the causation of MS. This study demonstrated that immunotherapy with EBV-specific T cells was associated with an improvement in patient symptoms and there was a reduction in disease activity on MRI with no side-effects.

From MSIF

Latest MS research news | 11 February 2014

Interaction between adolescent obesity and HLA risk genes in the etiology of MS

This study looked at the potential interaction between adolescent obesity and the genes most strongly associated with MS. The researchers found interactions between adolescent obesity and two potent MS risk genes.

From MSIF

Latest MS research news | 04 February 2014

Apolipoproteins are associated with new MRI lesions and deep grey matter atrophy in clinically isolated syndromes

This study investigated if the serum levels of apolipoproteins (which are types of proteins involved in cholesterol regulation) measured prior to starting disease modifying therapy were associated with disease progression

From MSIF

Latest MS research news | 04 February 2014

Pregnancy outcomes in the clinical development program of fingolimod in MS

This study reports the outcomes of women with unplanned pregnancies who enrolled in fingolimod (new oral treatment available in relapsing remitting MS) clinical trials.

From MSIF

Latest MS research news | 04 February 2014

Lower urinary tract symptoms and urodynamic dysfunction in clinically isolated syndromes suggestive of MS

Urinary tract symptoms are common in MS, with a significant negative impact on quality of life. This study demonstrated that patients with clinically isolated syndrome (CIS) had a higher prevalence of urinary symptoms.

From MSIF

Latest MS research news | 28 January 2014

Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS

This study looked at particular types of immune cells (T cells), which are known to cause injury to the central nervous system in RRMS, although their role in SPMS is not clear. The researchers found that there were differences in the cell biology of these T cells, which identified patients with MS having different rates of development of secondary progression.

From MSIF
 

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