Latest MS research news

Latest MS research news | 29 October 2013

Effects of exercise on fitness and cognition in progressive MS: a randomised, controlled pilot trial

This pilot randomised-controlled trial looked at the potential benefit of standardised exercise as a therapeutic intervention in progressive MS.

From MSIF

Latest MS research news | 21 October 2013

Teriflunomide versus subcutaneous interferon beta-1a in patients with RRMS: a randomised, controlled phase 3 trial

Teriflunomide selectively and reversibly inhibits dihydro-orotate dehydrogenase (DHODH). DHODH is a mitochrondrial enzyme involved in pyrimidine synthesis required by ...

From MSIF

Latest MS research news | 21 October 2013

Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with MS

This study looked at the changes in total lymphocyte counts (TLCs) in the peripheral blood of 23 people with MS receiving fingolimod for four to seven years, as well as the association between TLCs and T-cell subsets ...

From MSIF

Latest MS research news | 21 October 2013

Ribosomal protein S6 mRNA is a biomarker upregulated in MS, downregulated by interferon treatment, and affected by season

In this Australian study, the researchers tested if T-cell activation gene expression pattern (TCAGE) in whole blood was replicated in an independent sample ...

From MSIF

Latest MS research news | 14 October 2013

Dalfampridine improves walking speed, walking endurance, and community participation in veterans with MS: a longitudinal cohort study

This longitudinal study looked at the tolerability as well as the effects of dalfampridine on walking and community participation.

From MSIF

Latest MS research news | 14 October 2013

A novel internet-based method of capturing outcomes in MS

This study from the UK looked at a novel internet-based method of capturing outcomes in 81 people with MS who were having EDSS assessments as part of clinical trials.

From MSIF

Latest MS research news | 14 October 2013

Lobar distribution of cortical grey matter lesions in MS clinical subgroups

This study looked at the lobar distribution of grey matter lesions as well as their relationship to the clinical course in MS.

From MSIF

Latest MS research news | 09 October 2013

The usefulness of brain MRI at onset in the differentiation of MS and seropositive NMO spectrum disorders

This retrospective study investigated if brain MRI at onset can be useful in the differentiation of MS and NMO spectrum disorders (NMOSD) in 51 people with MS and 67 anti-aquaporin4-antibody-positive ...

From MSIF

Latest MS research news | 09 October 2013

Season of infectious mononucleosis and risk of MS at different latitudes: the EnvIMS Study

The worldwide distribution of MS strongly indicates a role for environmental factors in the development of MS. Epstein Barr Virus (EBV) is one possible causative agent ...

From MSIF

Latest MS research news | 09 October 2013

Gene expression analysis of relapsing-remitting, primary progressive and secondary progressive MS

This study from Denmark investigated if different MS subtypes would show differences in gene expression which may be linked to specific subsets of peripheral blood mononuclear cells (PBMCs).

From MSIF
 

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Atacicept in multiple sclerosis: a randomised, placebo-controlled, double-blind, phase 2 trial