Latest MS research news

Latest MS research news | 30 September 2013

Circulating dendritic cells of MS patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors

Dendritic cells (DC) are innate immune cells and may play a role in the pathogenesis of MS. Due to their specialised antigen-presenting capacity; DCs provide an important link ...

From MSIF

Latest MS research news | 24 September 2013

Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis

The primary question the research group addressed was if perfusion MRI in early RRMS might detect a reduction in grey matter (GM) perfusion in the absence of GM atrophy, which may potentially indicate a reversible ...

From MSIF

Latest MS research news | 24 September 2013

Natalizumab affects the T-cell receptor repertoire in patients with multiple sclerosis

This study from Sweden looked at the changes in the T-cell receptor (TCR) repertoire in both CSF and peripheral blood in people with MS treated with natalizumab for at least 18 months.

From MSIF

Latest MS research news | 24 September 2013

Global N-acetylaspartate concentration in benign and non-benign multiple sclerosis patients of long disease duration

N-acetylasparate (NAA) is a neuronal marker. Based on this, the researchers in the study examined if people with benign MS (BMS) had similar losses of global NAA relative to more ...

From MSIF

Latest MS research news | 17 September 2013

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage

The original phase III trial looked at oral laquinimod in 1106 people with RRMS.

From MSIF

Latest MS research news | 17 September 2013

Brain atrophy and lesion load predict long term disability in multiple sclerosis

This retrospective study as part of the MAGNIMS collaboration looked at MR imaging at baseline and after one year and two years as well as EDSS scores at baseline and after ten years in 261 people with MS.

From MSIF

Latest MS research news | 17 September 2013

Comparing long-term results of PASAT and SDMT scores in relation to neuropsychological testing in multiple sclerosis

This study from the Netherlands looked at the validity and reliability over time of the Symbol Digit Modality Test (SDMT) and the Paced Auditory Serial Addition Test (PASAT) ...

From MSIF

Latest MS research news | 10 September 2013

Randomised controlled trial of a behavioural intervention targeting symptoms and physical activity in multiple sclerosis

This study group looked at promoting lifestyle physical activity in MS.

From MSIF

Latest MS research news | 10 September 2013

Treatment effect on brain atrophy correlates with treatment effect on disability in multiple sclerosis

The researchers in this study evaluated the extent to which treatment effect on brain atrophy is able to mediate the effect on disability progression in RRMS at the clinical trial level.

From MSIF

Latest MS research news | 10 September 2013

Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development

This study looked at the plasma levels of osteopontin (OPN) in 492 people with MS, in order to evaluate its potential as a biomarker for disease ...

From MSIF
 

Latest MS research news

Main MS research areas

Challenges of MS research