Lifestyle profile of people at the time of their first clinical demyelinating event: results from Ausimmune study

This multi-centre incident case-control study from Australia examined the lifestyle profile of people at the time of their first clinical demyelinating event (FCD), prior to a diagnosis of established MS, compared to age, sex and regionally matched young adults. Exposures measured included current and past tobacco and marijuana, alcohol and beverage use, physical activity patterns, blood pressure and physical anthropometry.

Results showed that a history of ever smoking was associated with FCD risk. Alcohol consumption was common and not associated with FCD risk. No case-control differences in blood pressure or physical anthropometry were observed.

In conclusion past tobacco smoking was positively associated with a risk of FCD but most other lifestyle factors were not. Prevention efforts against type 2 diabetes and cardiovascular disease by increasing physical activity and reducing obesity are unlikely to alter MS incidence.

Authors: Ponsonby AL, Lucas RM

Source: Mult Scler. 2013 May 13. [Epub ahead of print]

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