MRI correlates of disability in African Americans with MS

This imaging study from the USA examines the differences in MRI appearances between Caucasian Americans and African Americans with MS which might explain the more aggressive form of the disease seen amongst African Americans. The authors found that there was no significant difference between the two ethnic groups in global and regional brain volumes but the lesion volume in African Americans was significantly greater. The authors therefore conclude that higher lesion accumulation rather than loss of brain volume is likely to account for the more rapid disease progression in African Americans.

Howard J, Battaglini M, Babb JS, Arienzo D, Holst B, Omari M, De Stefano N, Herbert J, Inglese M.

PLoS One. 2012;7(8):e43061. Epub 2012 Aug 10.

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