In this 5-year longitudinal MS cohort study from the USA, the
authors followed up 469 patients with relapsing-remitting MS on an
annual basis and found an inverse relationship between serum vitamin D
levels and the risk of developing new T2 lesions on brain MRI.
Furthermore each 10ng/ml higher vitamin D level was associated with
lower subsequent disability and there was a non-statistically
significant trend towards lower relapse rates in patients with higher
vitamin D. The authors suggest that these results provide further
support for a randomised trial of vitamin D supplementation.
Authors: Mowry EM, Waubant E, McCulloch CE,
Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC,
Qualley P, Bucci M, Hauser SL, Pelletier D.
Source: Ann Neurol. 2012 Aug;72(2):234-40. doi: 10.1002/ana.23591.
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